Прегледај по Аутор "Čančar, Vladimir"

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    Factors Associated with Abnormal Uterine Bleeding in Perimenopausal Women
    (IMR Press Limited, 2024) Ivanović, Radenko; Joksimović, Bojan; Čančar, Vladimir; Marić, Helena; Matović, Draženka; Lalović, Nenad; Pavlović, Radiša; Milosavljević, Miloš; Milosavljević, Jovana; Janković, Slobodan
    Background: Abnormal uterine bleeding (AUB) is one of the most common health problems encountered in women of the perimenopausal age group. The aim of this study was to investigate the characteristics of functional AUB in perimenopausal women, and to identify predictors of the occurrence of functional AUB in perimenopausal women. Methods: This was a cross-sectional study that included 45 women with complaints of AUB admitted to the gynecology ward in the University Hospital in Foča, and 45 women without AUB who underwent a gynecological examination in the Primary Health Center in Foča, Bosnia and Herzegovina. We included women with AUB who had a normal ultrasound finding without obvious genital or cervical lesions, and who were not on hormonal therapy. The existence of AUB was determined on the basis of a clinical examination by a gynecologist and existing medical documentation. A logistic regression model was used to assess the possible relationship between the occurrence of the functional AUB and the risk factors for its occurrence. Results: The mean patient age was 48.38 ± 2.40 years. There was no significant difference in age, frequency of physical activity, or previous use of oral contraceptives between the two groups of patients divided by the presence of the functional AUB in perimenopause. The logistic regression model showed that age (p = 0.008), high values of body mass index (BMI) (p = 0.001), consumption of alcohol and cigarettes on a daily basis (p = 0.001), and hypertension (p = 0.046) represented significant risk factors associated with functional AUB in perimenopausal women. Conclusions: During routine exams of women approaching menopause, gynecologists should emphasize the harms of smoking and alcohol use, as well as the significance of non pharmacological and pharmacological methods for the treatment of obesity and hypertension
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    Paraovarian cyst as the cause of uterine prolapse
    (Institute of Oncology, Sremska Kamenica, 2021) Čančar, Vladimir; Ivanović, Radenko; Lalović, Nenad; Milinković, Biljana; Sladoje, Dragana
    Paraovarian cysts originate from the mesothelium and are presumed to be remnants of Müllerian or Wolffian ducts. In majority of cases they are found to be 10-80 mm in diameter and do not cause any symptoms. Paraovarian cysts can be found unexpectedly during an operation or on ultrasound examination performed for other reasons. They are most freequently discovered on ultrasound examination. However, due to the proximity of the ovary for which cystic formations are not rare, the diagnosis of these lesions can be a challenge. They are mostly asymptomatic and only large lesions (≤20 cm in diameter) become symptomatic. Although these are mostly benign tumors, in rare cases they can become borderline or true malignancies. Most paraovarian cysts are found in the third and fourth decade of life. Paraovarian cyst complications include: compression of the surrounding structures of the pelvis minor and abdomen, pelvic pain, cyst torsion and rupture. Except for the already mensioned complications available literature has so far failed to show cases of uterine prolapse caused by an increase of intra-abdominal pressure due to the expansive growth of giant paraovarian cystic formation.
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    Survival analysis of patients with rare tumors of the uterine corpus – carcinosarcomas
    (Institute for Military Medical Scientific Information, 2024) Stevanović, Nemanja; Mandić, Aljoša; Maričić, Slobodan; Nadj, Gabriel Stefan; Maksimović, Tamara; Stanulović, Nevena; Čančar, Vladimir; Rodić, Milan
    Background/Aim. Uterine carcinosarcoma (UCS), former-ly known as malignant mixed Müllerian tumor, is a rare, ag-gressive malignancy of the female genital tract. The aim of this study was to analyze the most important clinical and pathohistological characteristics of UCSs on operated pa-tients, as well as to determine which of those factors are af-fecting progression-free survival (PFS) and overall survival (OS) of patients. Methods. The study was conducted as a retrospective analysis of medical data documentation of pa-tients with a diagnosis of UCS who were surgically treated at the Department of Gynecology, Clinic for Operative On-cology, Oncology Institute of Vojvodina, Sremska Kameni-ca, Serbia, in 10 years’ period (from the beginning of 2009 to the end of 2018). The analysis included data for a total of 31 patients. Results. Of all the examined parameters (age of the patient, clinical stage of the disease, histological grade, depth of myometrial invasion, and lymphovascular invasion – LVI), the greatest influence on the choice of therapeutic procedure had a histological tumor grade. Conclusion. Our research showed the joint influence of the examined clinical and pathohistological factors on PFS and OS of patients with UCS. The only independent parameter that showed a statistically significant impact on survival is LVI.