Прегледај по Аутор "Šuljagić, Vesna"
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- СтавкаA nationwide assessment of the burden of healthcare‑associated infections and antimicrobial use among surgical patients: results from Serbian point prevalence survey, 2017(Springer, 2021) Šuljagić, Vesna; Bajčetić, Milica; Mioljević, Vesna; Dragovac, Gorana; Mijović, Biljana; Janićijević, Ivana; Đorđević, Zorana; Krtinić, Gordana; Rakić, Violeta; Ćirković, Ivana; Nikolić, Vladimir; Marković‑Denić, LjiljanaBackground: As the only non-European Union (EU) country, Serbia participated in a second point prevalence survey of healthcare-associated infections (HAIs) and antimicrobial use (AMU) organized by the European Centre for Disease Prevention and Control (ECDC) in the EU countries. Here, we aimed to estimate the prevalence of HAI and AMU in patients who had recently undergone a surgery and to compare risk profile, HAI rates, and AMU among surgical patients and non-surgical patients. Methods: A national PPS was performed in 65 Serbian acute-care hospitals, in November 2017. In this paper, the data of 61 hospitals for adult acute-care were analyzed. To ensure the comparability of study design we used the Serbian translation of ECDC case definitions and ECDC PPS protocol. The trained infection control staff, led by a hospital coordinator, reviewed medical records to identify HAI active at the time of the survey and AMU. Only inpatients admitted to the ward before 8 a.m. on the day if the survey were included. Results: A total of 12,478 patients from 61 hospitals for adult acute-care were eligible for inclusion in this study. Significantly higher proportions of surgical patients were female, belonged to the 60-to-79 age group, and were less severely ill. Also, extrinsic factors (invasive devices, hospitalization at the ICU, and prior antibiotics therapy) were more frequent in surgical patients. Prevalence of HAIs was higher among surgical patients (261/3626; 7.2%) than among non-surgical patients (258/8852; 2.9%) (p < 0.0001). The highest prevalence of all HAIs was noted in patients who had kidney transplantation (4/11; 36.4%), while SSIs were the most prevalent among patients who had peripheral vascular bypass surgery (3/15; 20.0%). Non-surgical patients received treatment for community-acquired infections in significantly higher proportion (2664/8852; 64.3) (p < 0.001). Surgical prophylaxis for more than 1 day was applied in 71.4% of surgical patients. Conclusion: We have provided an insight into the burden of HAIs and AMU among Serbia acute-care hospitals, and highlighted several priority areas and targets for quality improvement
- СтавкаRisk factors for Clostridium difficile infection in surgical patients hospitalized in a tertiary hospital in Belgrade, Serbia: a case–control study(Springer, 2017) Šuljagić, Vesna; Miljković, Ivan; Starčević, Srđan; Stepić, Nenad; Kostić, Zoran; Jovanović, Dragutin; Brusić-Renaud, Jelena; Mijović, Biljana; Šipetić-Grujičić, SandraBackground: The objective of this study was to investigate independent risk factors (RFs) connected with healthcare-associated (HA) Clostridium difficile infection (CDI) in surgical patients, its frequency per surgical wards and in-hospital-mortality at a single hospital. Methods: Risk factors for the infection were prospectively assessed among surgical patients with laboratory confirmed HA CDI and compared with a control group without HA CDI. Results: The overall incidence rate of HA CDI was 2.6 per 10000 patient-days. Significant independent RFs for HA CDI were the use of carbapenems (P = 0.007, OR: 10.62, 95% CI: 1.93–58.4), the admission to intensive care unit (P = 0.004, OR:3.00, 95% CI:1.41–6.40), and the administration of 3rd generation cephalosporins (P = 0.014, OR:2.27, 95% CI:1.18–4.39). Patients with HA CDI had significantly higher in–hospital mortality compared to controls (P: 0.007; OR: 8.95; 95% CI: 1.84–43.43). Conclusions: CDI is an important HA infection in population of surgical patients and this study emphasizes the importance of the wise use of antibiotics, and other infection control strategies in order to prevent HA CDI, and to decrease the incidence and in-hospital mortality rate.
- СтавкаSurgical site infection surveillance in orthopedic patients in the Military Medical Academy, Belgrade(Ministry of Defance, Serbia, 2015) Starčević, Srdjan; Munitlak, Staša; Mijović, Biljana; Mikić, Dragan; Šuljagić, VesnaBackground/Aim. Active surveillance is an important com-ponent of surgical site infection (SSI) reduction strat-egy. The aim of this study was to analyze and compare SSI surveillance data in orthopedic patients in the Military Medical Academy (MMA), Belgrade. Methods. A 4-year prospective cohort study was performed to identify the in-cidence rate and risk factors for SSI in orthopedic patients in the MMA, Belgrade. We col-lected data regarding pa-tients characteristics, health care and micro-organisms iso-lated in SSI. The National Nosocomial In-fection Surveil-lance (NNIS) risk index was subsequently calcu-lated for each patient. The Centers for Disease Control and Preven-tion criteria were used for the diagnosis of SSI. Re-sults. Assessment of 3,867 patients after different orthopedic operations revealed SSI in 109 patients. The overall incidence rate of SSI was 2.8% with the decrease from 4.6% in 2007 to 1.6% in 2010. Using NNIS risk index for surgical procedures there were: 53.7% (2,077) patients with risk 0 – the incidence rate of 1.4%; 38.9% (1,506) patients with risk 1 – the incidence rate of 3.1%; 7.3% (281) patients with risk 2 – the incidence rate of 11.7%; 0.1% (3) patients with risk 3 – without infection within the risk. Multivariate logistic regression analysis identi-fied 6 independent risk factors associated with SSI: contami-nated or dirty wounds, smoking, preoperative infection, NNIS risk index, body mass index and the length of hospital stay. Conclusion. The results of our study are valuable confirma-tion of relations between risk factors and SSI in orthopedic pa-tients. A decreasing incidence rate of SSI (from 4.6% to 1.6%) during a 4-year active surveillance approved its implementation as an important component of SSI reduction strategy.