Прегледај по Аутор "Davidovic, Bojana"
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- СтавкаIncreased systemic sST2 in patients with end stage renal disease contributes to milder liver damage during HCV infection(2020) Lukic, Ruzica; Cupic, Majа; Gajovic, Nevena; Jurisevic, Milena; Mijailovic, Zeljko; Davidovic, Bojana; Kujundžic, Bojan; Joksimovic, Bojan; Arsenijevic, Nebojša; Jovanovic, IvanIntroduction: Hepatitis C Virus (HCV) is the leading cause of chronic liver disease and is a serious global health problem. Hepatitis C infection is highly prevalent in patients with end stage renal disease (ESRD), due to frequent exposure to blood and blood products, nosocomial transmission of HCV, and prolong hemodialysis duration. The aim of the study was to evaluate the influence of IL-33/ST2 signaling pathway on severity of the liver disease in ESRD HCV+ patients. Methodology: Blood samples from patients with end stage renal disease (ESRD) and hepatitis C infection (HCV), 20 patients with HCV infection, 20 patients with ESRD and 20 healthy control donor patients were taken for the examination of biochemical parameters, for the determination of the serum cytokine concentration, and for the molecular diagnostics of HCV. Results: Systemic sST2 positively correlated with serum level of urea and creatinine, respectively. Serum sST2 was significantly increased in ESRD HCV+ patients in comparison to HCV+ group. sST2/IL-1, sST2/IL-4 and sST2/IL-23 ratios were significantly increased in serum of ESRD HCV+ patients in comparison to HCV+ patients. Significantly higher systemic level of sST2 and sST2/IL-1 and sST2/IL-4 ratios were measured in ESRD patients compared to non-ESRD patients. Conclusion: These results suggested that elevated level sST2, as the consequence of renal failure, causes less destruction of liver in HCV infection
- СтавкаThe Role of Artificial Intelligence in the Accurate Diagnosis and Treatment Planning of Non-Syndromic Supernumerary Teeth: A Case Report in a Six-Year-Old Boy(MDPI, 2023) Mladenovic, Rasa; Kalevski, Katarina; Davidovic, Bojana; Jankovic, Svjetlana; Todorovic, Vladimir S.; Vasovic, MiroslavHyperdontia can cause numerous aesthetic and functional problems. The diagnosis is made radiologically, and the most commonly used radiological method is orthopantomography, while CBCT is also used. CBCT has the advantage of being three-dimensional. Artificial Intelligence is widely used in medicine and dentistry, and it can create a specific algorithm to aid in diagnosis and suggest therapeutic procedures. In a case report, a 6-year-old boy was diagnosed with a supernumerary tooth between the upper central incisors. Orthopantomography revealed another impacted supernumerary tooth, and the patient was referred for CBCT. A platform for analyzing dental images, based on artificial intelligence, Diagnocat (Diagnocat Inc., San Francisco, CA, USA), was used for analysis and the AI system identified the supernumerary teeth and provided a complete plan for treatment. The use of AI in dentistry allows for faster and more accurate diagnosis and treatment planning