Прегледај по Аутор "Maksimović, Tamara"

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    Survival analysis of patients with rare tumors of the uterine corpus – carcinosarcomas
    (Institute for Military Medical Scientific Information, 2024) Stevanović, Nemanja; Mandić, Aljoša; Maričić, Slobodan; Nadj, Gabriel Stefan; Maksimović, Tamara; Stanulović, Nevena; Čančar, Vladimir; Rodić, Milan
    Background/Aim. Uterine carcinosarcoma (UCS), former-ly known as malignant mixed Müllerian tumor, is a rare, ag-gressive malignancy of the female genital tract. The aim of this study was to analyze the most important clinical and pathohistological characteristics of UCSs on operated pa-tients, as well as to determine which of those factors are af-fecting progression-free survival (PFS) and overall survival (OS) of patients. Methods. The study was conducted as a retrospective analysis of medical data documentation of pa-tients with a diagnosis of UCS who were surgically treated at the Department of Gynecology, Clinic for Operative On-cology, Oncology Institute of Vojvodina, Sremska Kameni-ca, Serbia, in 10 years’ period (from the beginning of 2009 to the end of 2018). The analysis included data for a total of 31 patients. Results. Of all the examined parameters (age of the patient, clinical stage of the disease, histological grade, depth of myometrial invasion, and lymphovascular invasion – LVI), the greatest influence on the choice of therapeutic procedure had a histological tumor grade. Conclusion. Our research showed the joint influence of the examined clinical and pathohistological factors on PFS and OS of patients with UCS. The only independent parameter that showed a statistically significant impact on survival is LVI.