Salivary flow rate and decayed, missing, and filled teeth (DMFT) in female patients with schizophrenia on chlorpromazine therapy

Једноставна страница ставке
dc.citation.epage424
dc.citation.spage418
dc.citation.volume8
dc.contributor.authorKrunić, Jelena
dc.contributor.authorStojanović, Nikola
dc.contributor.authorIvković, Nedeljka
dc.contributor.authorStojić, Dragica
dc.date.accessioned2023-09-07T10:41:10Z
dc.date.available2023-09-07T10:41:10Z
dc.date.issued2013
dc.description.abstractBackground/purpose: The purpose of the study was to investigate relationship between saliva flow rates, estrogen levels, and caries prevalence in female psychiatric patients under antipsychotic therapy. Materials and methods: Sixty-one institutionalized psychiatric females (31 patients treated with chlorpromazine only and 30 patients treated with chlorpromazine and biperiden) were compared with 36 unmedicated healthy females. The unstimulated whole saliva (UWS) flow rate and serum estrogen were measured. Caries prevalence was recorded in terms of decayed, missing, and filled teeth (DMFT). Results: The UWS flow rate in the control group was 0.35 0.18 mL/min and the DMFT 18.8 5.7. In comparison, UWS flow rates were 0.25 0.15 mL/min (P Z 0.003) and 0.07 0.05 mL/min (PZ 0.000) in patients on chlorpromazine and patients on chlorpromazine as well as biperiden, respectively, and DMFT values were 22.7 4.6 (P Z 0.003) and 26.5 5.3 (P Z 0.000), respectively. Patientson chlorpromazinewithamenorrheahad reducedUWS flowrate and estrogenlevels with respect to controls (PZ0.036; PZ0.000, respectively). Correlation analysis revealed significant correlations betweenUWS flow rate and DT, DMFT, number of used drugs and estrogen level. Conclusion: It seems that chlorpromazine-induced hyposalivation included (apart from its antimuscarinic effect) a neuroendocrine effect which affected the estrogen levels.
dc.identifier.doi10.1016/j.jds.2013.05.004
dc.identifier.urihttps://vaseljena.ues.rs.ba/handle/123456789/715
dc.language.isoen
dc.publisherElsevier
dc.sourceJournal of Dental Sciences
dc.subjectbiperiden; chlorpromazine; DMFT; estrogen; saliva secretion
dc.titleSalivary flow rate and decayed, missing, and filled teeth (DMFT) in female patients with schizophrenia on chlorpromazine therapy
dc.typeArticle
Датотеке
Оригинални завежљај
Сада се приказује 1 - 1 од 1
Сличица
Име:
Salivary flow rate and decayed, missing, and filled teeth (DMFT) in female patients with schizophrenia on chlorpromazine therapy.pdf
Величина:
311.06 KB
Формат:
Adobe Portable Document Format
Опис:
Преузимање
Свежањ лиценце
Сада се приказује 1 - 1 од 1
Сличица
Име:
license.txt
Величина:
1.71 KB
Формат:
Item-specific license agreed to upon submission
Опис:
Преузимање
Колекције
Медицински факултет [Научни радови] / Faculty of Medicine [Scientific papers]