Прегледај по Аутор "Golijanin, Ranko"
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- СтавкаCOMPARATIVE POSTOPERATIVE ANALGESIA WITH FEMORAL NERVE BLOCK ”3-IN-1” AND WITH FASCIA ILIACA COMPARTMENT NERVE BLOCK AFTER HIP ALLOARTHROPLASTY(Serbian Medical Society, Section Kragujevac, 2016) Lončar Stojiljković, Dragana; Stojiljković, Miloš P.; Golijanin, Ranko; Novaković Bursać, Snježana; Škrbić, RankoObjective. Hip arthroplasty is one of the most common operations in elderly population. Pre- and postoperative risks increase their postoperative morbidity and mortality. One of the most important factors, which is included in the perioperative risks, is pain. Control of postoperative pain diminishes the incidence and severity of complications afterwards. Methods. We compared three different techniques of pain control in 30 patients scheduled for elective hip arthroplasty: 1) pharmacological – morphine 5 or 10 mg iv q6h, depending on body weight, paracetamol 1 g i.v. q6h (MP), 2) nerve block: femoral nerve block, single shot (FNB) and 3) fascia iliaca compartment nerve block (FICNB). Measurement of pain intensity was performed with numerical pain scale (NPS). Systolic blood pressure and consumption of additional analgesics on demand were monitored, as well as the duration of nerve blocks. Results. Both nerve blocks produced significantly lower pain scores than the purely pharmacological approach (MP 5.4+0.6 vs. FNB 2.8+1.6 and FICNB 2.9+1.2 after the first postoperative hour). Consequently, the first group required more additional morphine and paracetamol after the first hour compared to FNB and FICNB groups. Morphine was significantly more frequently added in the MP group (3.4+0.4 mg/kg IV) than in the FNB (2.1+0.5 mg/kg i.v.) and FICNB (2.5+0.4 mg/kg i.v.). Maximal duration of analgesia was 5 hours in MP group compared to 9 and 8 hours after FNB and FICNB, respectively. Conclusion. Postoperative analgesia with blocks enables better pain control, better cardiovascular stability and less adverse effect than the classical morphine-based analgesia.
- СтавкаDENTAL FOCAL INFECTIONS AND ALOPECIA AREATA(Serbian Medical Association Kragujevac district branch, 2015) Regoje, Dobrila; Golijanin, Ranko; Pinjic, Omer; Obrenovic, Miroslav; Kujundzic, BojanObjective. The aim of this study was to examine the association of dental focal infections and alopecia areata in the adult population. Methods. The research was done in a medical institution, “Dermato-dento-medik Brcko dr Regoje”, and the Clinic for Dermatovenerology of University Clinical Center, Tuzla. The study included 63 patients which were treated surgically and medically according to the current therapeutic guidelines. All patients were divided into three groups. The first group of patients suffering from alopecia areata were treated only surgically, by removing the focus. In the second group there were patients who were treated by removing the focus and local dermatological therapy (most of them had periodontal disease). In the third group there were patients who were treated only with local dermatological therapy (most of them had gingival hyperplasia). Results. In total of 41 subjects the changes of alopecia areata had affected the hairy part, while 22 patients had changes on the chin. The difference in distribution, in relation to the expected even distribution, was statistically significant (2=5.7, df=1, p=0.017). However, the difference concerning the observed distribution of lesion in hairy parts and in other location between the three study groups was not statistically significant (2=0.2, df=1, p=0.676). Analysis of the outcomes of treatment for alopecia areata showed the highest effectiveness in the second group (n=21) because the hair growth appeared after 4 to 6 weeks after the initiation of the therapy. In the first group (n=20) the hair growth appeared within 6 to 8 weeks, and in the third group there was no hair growth during the monitoring period up to 8 weeks. Conclusion. Our study present novel data about relationships between dental focal infections and alopecia areata with outcomes after surgical and medical treatment, respectively.
- СтавкаFREQUENCY OF SPECIFIC PATHOLOGICAL PROCESSES – FOCAL DENTAL INFECTIONS IN PATIENTS WITH ALOPECIA AREATA(Serbian Medical Association Kragujevac district branch, 2015) Regoje, Dobrila; Golijanin, Ranko; Pinjić, Omer; Obrenović, Miroslav; Kujundžić, Bojan; Miletić, NatašaThe aim of this study was to determine the frequency of specific pathological processes on teeth in patients with alopecia areata. The research was done in medical-esthetic center "Dermato-dentomedik" in Brcko and the Clinic for Dermatovenerology of University Clinical Center, Tuzla. The study included 75 patients which were divided into three groups. The first group consisted of patients suffering from alopecia areata treated only surgically. The second group consisted of patients suffering from alopecia areata treated with surgical and local dermatological therapy. The third group included patients suffering from alopecia areata treated only with dermatological therapy. In the first group of patients (n = 20) who were treated only by removing the focus, the most common pathological processes were chronic apical lesions and cysts (30%). In the second group of patients (n = 27) who were treated by removing the focus and local dermatological therapy the most frequent was periodontal disease with 29.6%. In the third group of patients (n = 26) who were treated with a local dermatological therapy, the most common pathological processes were chronic apical lesions (38.5%), cysts (26.9%) and periodontal (19.2%). Our study presents the frequency of pathological odontogenic focus in alopecia areata, with the importance of a common multidisciplinary approach to treatment which can be accomplished the greatest success in the treatment of alopecia areata.
- СтавкаMorphometric analysis of collagen and inflammatory cells in periodontal disease(University of Defence - Faculty of Medicine of the Military Medical Academy, 2015) Golijanin, Ranko; Kujundžić, Bojan; Milosavljević, Zoran; Milovanović, Dragan R.; Andjelković, Zlatibor; Obrenović, Miroslav; Nikolić, RadivojeBackground/Aim. Periodontal disease affects gingival tissue and supporting apparatus of the teeth leading to its decay. The aim of this study was to highlight and precisely determine his-tological changes in the gum tissue. Methods. Gingival biopsy samples from 53 healthy and parodontopathy-affected patients were used. Clinical staging of the disease was performed. Tissue specimens were fixed and routinely processed. Sections, 5 μm thin, were stained with hematoxylin and eosin, histochemical Van-Gieson for the collagen content, Spicer method for mast-cells and immunochemical method with anti-CD68 and anti-CD38 for the labelling of the macrophages and plasma-cells. Morphometric analysis was performed by a M42 test system. Results. While the disease advanced, collagen and fibroblast volume density decreased almost twice in the severe cases compared to the control ones, but a significant variation was observed within the investigated groups. The mast-cell number increased nearly two times, while the macrophage content was up to three times higher in severe parodontopathy than in healthy gingival tissue. However, the relative proportion of the-se cells stayed around 6% in all cases. Plasma-cells had the most prominent increase in the number (over 8 times) com-pared to the control, but again, a variation within investigated groups was very high. Conclusion. Gingival tissue destruction caused by inflammatory process leads to significant changes in collagen density and population of resident connective tissue cells. Although inflammatory cells dominated with the disease advancing, a high variation within the same investigated groups suggests fluctuation of the pathological process.