Прегледај по Аутор "Trbojević, Stevan"
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- СтавкаEffects of protamine sulphate on spontaneous and calcium-induced contractile activity in the rat uterus are potassium channels-mediated(Slovak Academy of Sciences, 2009) Oreščanin-Dušić, Zorana; Milovanović, Slobodan; Radojičić, Ratko; Nikolić-Kokić, Aleksandra; Appiah, Isabella; Slavić, Marija; Čutura, Neđo; Trbojević, Stevan; Spasić, Mihajlo; Blagojević, DuškoProtamine sulphate (PS) effect on spontaneous and calcium-induced rhythmic contractions of isolated virgin rat uteri was studied. PS caused dose-dependent relaxation of both types of contractions (two-way ANOVA, significant dose effects). Pretreatment with NG-nitro-L-arginine methyl ester (L-NAME; 10–5 mol/l), methylene blue (MB; 0.9 × 10–6 mol/l) or propranolol (1.7 × 10–5 mol/l) enhanced PS-mediated uterine muscle relaxation of spontaneous contractions. Dosedependent relaxation of spontaneous active isolated rat uterus with PS was lower in uteri pretreated with single dose of tetraethylammonium (TEA; 6 × 10–3 mol/l), glibenclamide (2 × 10–6 mol/l) and 4-aminopyridine (4-AP; 10–3 mol/l). Calcium-induced activity of the isolated rat uterus pretreated with the same concentration of L-NAME, MB, or propranolol modified the kinetic of PS-induced relaxation without changes in EC50 values. Pre-treatment with glibenclamide, TEA and 4-AP significantly reduce PS relaxing effect of calcium-induced activity and according to EC50 values the order of magnitude was glibenclamide > TEA > 4-AP. PS is mixture of polyamines and may activate different signal-transduction pathways. Our results cleary demonstrate that in uterine smooth muscle PS act dominantly through potassium chanels and marginaly through β-adrenergic receptos or nitric oxide-dependent pathways.
- СтавкаInfluence of Realization of Prepositions and Prepositional Phrases on Their Proper Use in Professional Medical Texts in English(University of Nis, Faculty of Medicine, Serbia, 2011) Krulj, Slobodanka; Prodanović, Bojana; Trbojević, StevanRealization of prepositions and prepositional phrases in professional medical texts in English may affect the proper selection of certain prepositions. Also, the use of prepositions is affected by literal translation into English. Today, the English language is the basic language for communication in biomedical sciences, and one of the problems that arises is the proper use of English by scientist non-native English speakers. A review of randomly selected medical professional journals and papers identified some typical misuse of prepositions that can be caused by different realizations of prepositions.
- СтавкаRealizations of Prepositions and Prepositional Phrases in Professional Medical Texts in English Language(University of Nis, Faculty of Medicine, Serbia, 2011) Krulj, Slobodanka; Prodanović, Bojana; Trbojević, StevanPrepositions and prepositional phrases play an important role in the professional medical register in English and they are very abundant. Realization of the prepositions in medical texts could cause difficulties to non-native English language speakers scientists. The subject of this paper is prepositions with their meanings (single and multiple). Preposition cannot appear independently and therefore we treated it together with its prepositional complement with which it forms prepositional phrases. In this paper we were not focused on the prepositional phrase functions within other sentence structures (phrases or clauses) but on internal relationship between preposition and its complement, especially on prepositions and prepositional phrase meanings in professional medical texts.