Прегледај по Аутор "Vukic, Milan"
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- СтавкаApplication of Biopolymers in the Food Industry.(Springer, 2017) Grujic, Radoslav; Vukic, Milan; Gojkovic, VesnaPlastic materials obtained from oil are used in the food industry. These polymers are cheap and available. They have good mechanical properties, good barriers for oxygen and vaporizable aromatic substances, and they can be hot welded. However, the main disadvantage is that biopolymers are not biodegradable, and certainly not environmentally friendly. That is the reason why the application of plastic materials must be limited and gradually replaced by materials that cause fewer ecological problems. Edible and biodegradable natural polymeric materials are one of the alternatives for food usage. These are made from polysaccharides, lipids, and proteins. Their application saves money that would otherwise need to be spent on environmental protection. Biodegradable natural polymeric materials can be used as edible films and coatings, packaging materials, carriers of antimicrobial and antioxidative materials, etc. Nanocomposites will be applied for food packaging in the future. Nanoscale research, including detection of a pathogen, active packaging, antimicrobial packaging, and the formation of barriers, will improve food packaging. It may be possible to use particles that are not organic to introduce diverse components such as colors and odors. They also may be used as tanks for the controlled release of drugs or fungicides.
- СтавкаEffect of Mastiha supplementation on NAFLD: The MAST4HEALTH Randomised, Controlled Trial(Wiley, 2021) Amerikanou, Charalampia; Kanoni, Stavroula; Kaliora, Andriana C.; Barone, Angela; Bjelan, Mladen; D’Auria, Giuseppe; Gioxari, Aristea; José Gosalbes, María; Mouchti, Sofia; Stathopoulou, Maria G.; Soriano, Beatriz; Stojanoski, Stefan; Banerjee, Rajarshi; Halabalaki, Maria; Mikropoulou, Eleni V.; Kannt, Aimo; Lamont, John; Llorens, Carlos; Marascio, Fernando; Marascio, Miriam; Roig, Francisco J.; Smyrnioudis, Ilias; Varlamis, Iraklis; Visvikis-Siest, Sophie; Vukic, Milan; Milic, Natasa; Medic-Stojanoska, Milica; Cesarini, Lucia; Campolo, Jonica; Gastaldelli, Amalia; Deloukas, Panos; Trivella, Maria Giovanna; Francino, M. Pilar; Dedoussis, George V.Scope Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease with poor therapeutic strategies. Mastiha possesses antioxidant/anti-inflammatory and lipid-lowering properties. The authors investigate the effectiveness of Mastiha as a nonpharmacological intervention in NAFLD. Methods and Results Ninety-eight patients with NAFLD in three countries (Greece, Italy, Serbia) are randomly allocated to either Mastiha or Placebo for 6 months, as part of a multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial. The authors assess NAFLD severity via magnetic resonance imaging (MRI) scanning and LiverMultiScan technique and evaluate the effectiveness of Mastiha through medical, anthropometric, biochemical, metabolomic, and microbiota assessment. Mastiha is not superior to Placebo on changes in iron-corrected T1 (cT1) and Liver Inflammation Fibrosis score (LIF) in entire patient population; however, after BMI stratification (BMI ≤ 35 kg m-2 and BMI > 35 kg m-2), severely obese patients show an improvement in cT1 and LIF in Mastiha versus Placebo. Mastiha increases dissimilarity of gut microbiota, as shown by the Bray-Curtis index, downregulates Flavonifractor, a known inflammatory taxon and decreases Lysophosphatidylcholines-(LysoPC) 18:1, Lysophosphatidylethanolamines-(LysoPE) 18:1, and cholic acid compared to Placebo. Conclusion Mastiha supplementation improves microbiota dysbiosis and lipid metabolite levels in patients with NAFLD, although it reduces parameters of liver inflammation/fibrosis only in severely obese patients.