ANTIOXIDANT AND CYTOTOXIC POTENTIAL OF SELECTED PLANT SPECIES OF THE BORAGINACEAE FAMILY

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dc.citation.epage61
dc.citation.spage53
dc.citation.volume67
dc.contributor.authorBOŠKOVIĆ, Ivana
dc.contributor.authorĐUKIĆ, Dragutin
dc.contributor.authorMANDIĆ, Leka
dc.contributor.authorMAŠKOVIĆ, Pavle
dc.contributor.authorGOVEDARICA-LUČIĆ, Aleksandra
dc.date.accessioned2023-09-20T10:33:43Z
dc.date.available2023-09-20T10:33:43Z
dc.date.issued2021
dc.description.abstractAntioxidant activity is one of the most important properties of plant extracts. Antioxidants from natural sources have been intensively studied in the last few decades. The antioxidant contents of medicinal plants may contribute to the protection of diseases. Bioactive components of plants have a potential role in chemoprevention and inhibition of different phases of the malignant transformation process. Therefore, plant extracts and essential oils are in the focus of research, and in recent decades have been tested on a large number of malignant cell lines. The aim of this study was to examine antioxidant and cytotoxic potential of selected plant species from the Boraginaceae family. Determination of antioxidant activity was performed by ammonium-thiocyanate method. Testing citotoxic activity was performed by MTT test on cancer cell lines: HEP 2c (human larynx carcinoma), RD (human cell line-rhabdomyosarcoma) and L2OB (mouse tumor fibroblast line). The best antioxidant activity showed ethanol, acetone and chloroform extracts of Anchusa officinalis, Echium vulgare and Echium italicum. The tested extracts showed an inhibitory effect on cancer cells, but chloroform and acetone extracts of all three plant had the most effective effect on L2OB cells. Isolation of individual active components from this plants and their testing for cancer cells would be of great importance for this field of research.
dc.identifier.doi10.17707/AgricultForest.67.2.04
dc.identifier.urihttps://vaseljena.ues.rs.ba/handle/123456789/811
dc.language.isoen
dc.publisherBiotechnical Faculty of the University of Montenegro
dc.sourceAgriculture & Forestry
dc.subjectantioxidans, cytotoxic potential, plant, extracts, Boraginaceae
dc.titleANTIOXIDANT AND CYTOTOXIC POTENTIAL OF SELECTED PLANT SPECIES OF THE BORAGINACEAE FAMILY
dc.typeArticle
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Пољопривредни факултет [Научни радови] / Faculty of Agriculture [Scientific papers]