EFFECT OF PROTAMINE SULFATE ON THE ISOLATED MESENTERIC ARTERIES OF NORMOTENSIVE AND SPONTANEOUSLY HYPERTENSIVE RATS

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dc.citation.epage168
dc.citation.spage163
dc.citation.volume60
dc.contributor.authorOREŠČANIN-DUŠIĆ, ZORANA
dc.contributor.authorMILOVANOVIĆ, S.
dc.contributor.authorSPASIĆ, M.
dc.contributor.authorRADOJIČIĆ, R.
dc.contributor.authorBLAGOJEVIĆ, D.
dc.date.accessioned2023-09-18T12:30:31Z
dc.date.available2023-09-18T12:30:31Z
dc.date.issued2008
dc.description.abstractWe tested the relaxant effect of increased protamine sulfate (PS) amounts (10, 20, 50, 100 and 150 μg/ml) on the isolated mesenteric arteries of normotensive and spontaneously hypertensive (SH) rats, with or without endothelium. PS caused concentration-dependent relaxation of isolated mesenteric arteries in both types of rats. The relaxation effect of PS was lower in SH rats than in normotensive ones. Our results indicate that the vascular smooth muscles play a significant role in PS-mediated relaxation.
dc.identifier.doi10.2298/ABS0802163O
dc.identifier.urihttps://vaseljena.ues.rs.ba/handle/123456789/796
dc.language.isoen
dc.publisherInstitute for Biological Research, Serbia
dc.sourceArchives of Biological Science Belgrade
dc.subjectProtamine sulfate, mesenteric artery, hypertension, vascular endothelium, rats
dc.titleEFFECT OF PROTAMINE SULFATE ON THE ISOLATED MESENTERIC ARTERIES OF NORMOTENSIVE AND SPONTANEOUSLY HYPERTENSIVE RATS
dc.typeArticle
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