Suppurative Thrombosis of the Portal Vein (Pylephlebits): A Systematic Review of Literature

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dc.citation.spage4992
dc.citation.volume11
dc.contributor.authorJevtic, Dorde
dc.contributor.authorGavrancic, Tatjana
dc.contributor.authorPantic, Ivana
dc.contributor.authorNordin, Terri
dc.contributor.authorW. Nordstrom, Charles
dc.contributor.authorAntic, Marina
dc.contributor.authorPantic, Nikola
dc.contributor.authorKaljevic, Marija
dc.contributor.authorJoksimovic, Bojan
dc.contributor.authorJovanovic, Milan
dc.contributor.authorPetcu, Emilia
dc.contributor.authorJecmenica, Mladen
dc.contributor.authorMilovanovic, Tamara
dc.contributor.authorSprecher, Lawrence
dc.contributor.authorDumic, Igor
dc.date.accessioned2023-05-10T10:35:39Z
dc.date.available2023-05-10T10:35:39Z
dc.date.issued2022
dc.description.abstractSuppurative portal vein thrombosis (pylephlebitis) is an uncommon condition usually associated with an intra-abdominal infection or inflammatory process. In this study, we aimed to synthesize data on previously published cases according to the PRISMA guidelines. A total of 103 patients were included. Patients were more commonly male (71.8%) and had a mean age of 49 years. The most common infection associated with pylephlebitis was diverticulitis (n = 29, 28.2%), and Escherichia coli was the most isolated pathogen (n = 21, 20.4%). Blood cultures were positive in 64 cases (62.1%). The most common site of thrombosis was the main portal vein (PV) in 59 patients (57.3%), followed by the superior mesenteric vein (SMV) in 40 patients (38.8%) and the right branch of the PV in 30 patients (29.1%). Sepsis developed in 60 patients (58.3%). The mortality rate in our review was 8.7%, and independent risk factors for mortality were the presence of pertinent comorbidities (OR 5.5, p = 0.02), positive blood cultures (OR 2.2, p = 0.02), and sepsis (OR 17.2, p = 0.049).
dc.identifier.doi10.3390/jcm11174992
dc.identifier.urihttps://vaseljena.ues.rs.ba/handle/123456789/119
dc.language.isoen
dc.publisherMDPI
dc.sourceJournal of Clinical Medicine
dc.subjectpylephlebitis; portal vein thrombosis; suppurative thrombosis of portal vein
dc.titleSuppurative Thrombosis of the Portal Vein (Pylephlebits): A Systematic Review of Literature
dc.typeArticle
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