Факултет физичког васпитања и спорта [Научни радови] / Faculty of Physical Education and Sport [Scientific papers]

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https://repozitorijum.ues.rs.ba/handle/123456789/51

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Прегледај Факултет физичког васпитања и спорта [Научни радови] / Faculty of Physical Education and Sport [Scientific papers] по Аутор "Alebić, Mirna"

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    Nanotechnology in medicine revolutionizing drug delivery for cancer and viral infection treatments
    (Elsevier, 2024) Karahmet Sher, Emina; Alebić, Mirna; Marković Boras, Marijana; Boškailo, Emina; Karahmet Farhat, Esma; Karahmet, Alma; Pavlović, Bojan; Sher, Farooq; Lekić, Lana
    Advancements in nanotechnology were vastly applied in medicine and pharmacy, especially in the field of nanodelivery systems. It took a long time for these systems to ensure precise delivery of very delicate molecules, such as RNA, to cells at concentrations that yield remarkable efficiency, with success rates reaching 95.0% and 94.5%. These days, there are several advantages of using nanotechnological solutions in the prevention and treatment of cancer and viral infections. Its interventions improve treatment outcomes both due to increased effectiveness of the drug at target location and by reducing adverse reactions, thereby increasing patient adherence to the therapy. Based on the current knowledge an updated review was made, and perspective, opportunities and challenges in nanomedicine were discussed. The methods employed include comprehensive examination of existing literature and studies on nanoparticles and nano-delivery systems including both in vitro tests performed on cell cultures and in vivo assessments carried out on appropriate animal models, with a specific emphasis on their applications in oncology and virology. This brings together various aspects including both structure and formation as well as its association with characteristic behaviour in organisms, providing a novel perspective. Furthermore, the practical application of these systems in medicine and pharmacy with a focus on viral diseases and malignancies was explored. This review can serve as a valuable guide for fellow researchers, helping them navigate the abundance of findings in this field. The results indicate that applications of nanotechnological solutions for the delivery of medicinal products improving therapeutic outcomes will continue to expand.