Optic neuritis in a teenage girl with granulomatosis with polyangiitis
Учитавање...
Датум
2021
Наслов журнала
Журнал ISSN
Наслов волумена
Издавач
Ministry of Defance, Serbia
Апстракт
Introduction. Granulomatosis with polyangiitis (GPA), formerly known as Wegener’s granulomatosis, is character-ized by necrotizing granulomatous inflammation in various tissues, including blood vessels, but primarily in the respira-tory tract and kidneys. Clinical manifestations can be di-verse, including inflammation of the eye and adnexa. Optic neuritis is a very rare ophthalmological manifestation of GPA, not previously described in a teenager. Case report. We presented a case of a 16-year-old girl with a rare extrap-ulmonary manifestation of GPA. The girl had a previous history of GPA and complained of a sudden blurred vision in the left eye. She was promptly referred to an ophthalmol-ogist who noted a decreased visual acuity of 20/400 in the left eye. Colour vision was impaired in the spectrum of red colour. Clinical examination revealed normal anterior seg-ment findings. On ophthalmoscopy, the left optic nerve oe-dema was noted. Urgent computed tomography of the left orbit showed a soft tissue mass around the optic nerve in the apex of the orbit. Magnetic resonance imaging con-firmed the diagnosis of optic perineuritis. After pulse doses of methylprednisolone, the girl achieved complete resolu-tion of vision in the left eye. Conclusion. If untreated, in-flammation of the optic nerve can lead to a permanent loss of vision. Prompt diagnostic and adequate treatment of pa-tients with GPA is needed in order to prevent vision-threatening complications and control the systemic disease
Опис
Кључне речи
diagnosis; optic nerve; optic neuritis; treatment outcome; wegener granulomatosis.